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| Zhejiang Kanglaite Pharmaceutical Co., Ltd. | ||||||
| About this company : Zhejiang Kanglaite Pharmaceutical Co., Ltd., established by Prof. Li Dapeng, is a “State Key High-tech Enterprise” . Covering an area of 7 hectares and a total floor space of 28,000 sq. m, the LVP production line and auxiliary equipment were introduced from Europe and USA. International GMP standard is strictly followed in production. There are over 500 staff of whom 60% are with university diploma. We have 32 regional offices in China. As “ State Basic Drug” and “State Medical Insurance Drug”, the company mainly produces botanical anticancer drug Kanglaite Injection (KLT) which is a novel dual-function and molecular targeted emulsion with active substance extracted from a TCM herb “semen coicis” . KLT has remarkable function in inhibiting and killing cancer cells while strengthening immune function. It has significant effectiveness in controlling cancerous pain, resisting cachexia, preventing cancer metastasis and recurrence, improving KPS, QOL and MST and effectively prolonging patient survival. KLT has full intellectual property. Its chemical component, process technology and application have obtained patent certificates from over 10 countries in the world. In 2001 FDA approved KLT to start clinical study in USA and the Russian Ministry of Health issued KLT registration certificate in December 2003. New pharmaceuticals like “Gingko Leave Soft Capsule”, “Co-Enzyme Q10” and fat emulsion have been added to the product catalogue in recent years. We are seeking overseas agent to distribute KLT with preferential policy. | ||||||
| Contact : Christopher Li, Director | ||||||
| Headquarters : 11th Rd. Xiasha Economic Zone,, Hangzhou, Zhejiang, 310018, China | ||||||
| Phone : 86-571-86911888ext1207, Fax : 86-571-86911680 | ||||||
| Website : Log on to trade instantly , Email : Log on to trade instantly | ||||||
.gif) | Kanglaite Injection KLT is a unique botanically sourced molecular targeted agent prepared as a micro-emulsion for intravenous use. It is manufactured by the state of art technology with active substance extracted from a natural herbal plant “semen coicis”. KLT has the following features. - Killing cancer cells directly and effectively while remarkably improving patient immune function; - Synergistic in increasing efficacy and in reducing toxicity when combined with chemotherapy regimens or radiation therapy; - Providing high energy nutrition to treat cachexia; - Relieving cancerous pain markedly; - Improving patient quality of life and notably prolonging survival; - With little adverse reaction itself In China KLT is mainly used in the following situation. - Combined with chemo regimens to minimize toxic reaction & enhance effect - Combined with radiotherapy to improve sensitivity - Preoperational monotherapy to prevent further spread and metastasis - Monotherapy after inefficacious chemotherapy to elevate KPS, MST and TTP, etc. - Treating late stage advanced and metastatic cases to elevate KPS, MST and TTP, etc. - Controlling cancerous pain with long lasting effect but without addiction - Improving cachexia to provide high energy nutrition - Applied in intervention with arterial perfusion in both large and small doses - Eliminating hydrothorax and pericardial effusion, etc. Standard treatment course for KLT is 200 ml (2 bottles) per day via intravenous drip x 42 days (84 bottles). There is a break for 4-5 days after 21 days. And clinical experiences in China and Russia suggest 2 treatment courses for those with late stage advanced and metastatic tumors for better therapeutic effect and evident prolongation of life. Based on pre-clinical studies at John Hopkins University, USA, tumor-inhibitive rate of KLT on transplanted breast carcinoma induced by cell strain MDA-MB-231 was over 50%. KLT could inhibit the expression of COX2 of the strain in vitro and act as an inhibitor of fatty acid synthase. The broad ranged basic studies in China also revealed KLT different mechanisms such as inducing cancer cell apoptosis, inhibiting angiogenesis, reversing MDR and regulating gene expression of Fas/Apo-1 and Bcl-2. Both Chinese and overseas clinical experiences have shown that KLT has proven effect in the treatment of cancers mainly at sites of lung, breast, liver, nasopharynx, esophagus, stomach, pancreas, kidney, colon-rectum, ovary and prostate. This agent is also applied in the treatment of malignant lymphoma and acute leukemia. KLT has brought great benefits to over 500,000 cancer patients in more than 2,000 big or medium hospitals in China since 1997. The year 1995 witnessed KLT patent certificates granted from China and USA, In August 1997 the phase III clinical study was successfully completed and the injection was officially launched in China after final approval from the Ministry of Public Health. FDA approved KLT clinical study in USA in March 2001 and the phase I study at Huntsman Cancer Institute, Salt Lake City, Utah was satisfactorily completed which laid a solid foundation for forthcoming clinical trials. The US "Science" magazine covered the success of KLT in China and USA in its January issue of 2003. The whole story in PDF format Russian Federation approved KLT clinical study in January 2002 and the phase II study was smoothly ended in April 2003 with inspiring outcomes. In December 2003 the registration certificate was issued from Russian Ministry of Health and KLT has been marketed in Russia from 2005 with positive response. Currently an international multi-center randomized clinical study on KLT combined with first line chemotherapeutic drugs in the treatment of non-small cell lung cancer (NSCLC) is in progress. | |||||
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